Top 10 tips to lose weight on low carb or keto for women 40+

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Top 10 tips to lose weight on low carb or keto for women 40+ - the evidence

This guide is written by Anne Mullens and was last updated on October 27, 2022. It was medically reviewed by Dr. Michael Tamber, MD on December 21, 2021.

The guide contains scientific references. You can find these in the notes throughout the text, and click the links to read the peer-reviewed scientific papers. When appropriate we include a grading of the strength of the evidence, with a link to our policy on this. Our evidence-based guides are updated at least once per year to reflect and reference the latest science on the topic.

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  1. Obstetrics & Gynecology Clinics of North America: The timing of the age at which natural menopause occurs [overview article; ungraded]

  2. It’s estimated that most women, without changing anything in their diet or lifestyle, gain an average of 2 to 5 pounds during the menopausal transition. However, some gain much more than this:

    Journal of Women’s Health 1998: The influence of sex hormones on obesity across the female life span [overview article; ungraded]

  3. This is based on clinical experience of low carb practitioners and was unanimously agreed upon by our low carb expert panel. You can learn more about our panel here [weak evidence].

  4. This is mainly based on clinical experience of low carb clinicians [weak evidence]

  5. Protein intake within this range has been shown to preserve muscle mass, improve body composition, and provide other health benefits in people who eat low carb diets:

    Peer J 2019: Low carbohydrate diets differing in carbohydrate restriction improve cardiometabolic and anthropometric markers in healthy adults: a randomised clinical trial [moderate evidence]

    Diabetes Therapy 2018: Effectiveness and safety of a novel care model for the management of type 2 diabetes at 1 year: an open-label, non-randomized, controlled study [weak evidence]

  6. British Journal of Nutrition 2020: The effect of 12 weeks of euenergetic high-protein diet in regulating appetite and body composition of women with normal-weight obesity: a randomised controlled trial [randomized trial; moderate evidence]

    Nutrition Journal 2014: Effects of high-protein vs. high- fat snacks on appetite control, satiety, and eating initiation in healthy women [randomized trial; moderate evidence]

    Journal of the American College of Nutrition 2004: The effects of high protein diets on thermogenesis, satiety and weight loss: a critical review [systematic review of randomized trials; strong evidence]

  7. Many experts in the field of protein and aging recommend a protein intake of at least 1.2 g/kg/day for older adults:

    Nutrients 2016: Protein consumption and the elderly: What is the optimal level of intake? [overview article; ungraded]

    In a 12-week trial of older adults who were frail or at high risk for frailty, participants who increased their protein intake to 1.5 g/kg/day achieved significant increases in muscle mass compared to those who consumed less protein:

    The American Journal of Clinical Nutrition 2018: Protein supplementation improves muscle mass and physical performance in undernourished prefrail and frail elderly subjects: a randomized, double-blind, placebo-controlled trial [randomized controlled trial; moderate evidence]

  8. Systematic reviews of randomized controlled trials exploring intermittent fasting have concluded that IF is at least equally effective for losing weight compared to continuous calorie restriction:

    Canadian Family Physician 2020: Intermittent fasting and weight loss: Systematic review [strong evidence]

    Obesity Reviews 2017: Short‐term intermittent energy restriction interventions for weight management: a systematic review and meta‐analysis [strong evidence]

    JBI Database of Systematic Reviews and Implementation Reports 2018: Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis [strong evidence]

  9. This is based on an individual clinician’s experience. [very weak evidence]

  10. Journal of Infusion Nursing 2014: Pathophysiology, treatment, and prevention of fluid and electrolyte abnormalities during refeeding syndrome
    [overview article; ungraded]

  11. This is based on clinical experience of low carb practitioners and was unanimously agreed upon by our low carb expert panel. You can learn more about our panel here [weak evidence].

  12.  [clinical experience; weak evidence]

  13. Part of the way low carb diets result in improved weight loss may be due to reduced hunger and overall calorie intake.

    A 2019 RCT reported reduced cravings with low carb diets

    Nutrients 2019: Changes in Food Cravings and Eating Behavior after a Dietary Carbohydrate Restriction Intervention Trial [randomized trial; moderate evidence]

    In several studies, limiting net carbs to less than 20 grams per day has been shown to  reduce appetite and intake, leading to weight loss without hunger:

    The American Journal of Clinical Nutrition 2008: Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum [randomized crossover trial; moderate evidence]

    Annals of Internal Medicine 2004: A low carbohydrate, ketogenic diet versus a low fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial [moderate evidence]

    Annals of Internal Medicine 2005: Effect of a low carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes [non-randomized trial; weak evidence]

    Nutrition & Metabolism 2005: A low carbohydrate, ketogenic diet to treat type 2 diabetes [non-randomized trial; weak evidence]

  14. Drinking alcoholic beverages can slow down weight loss because your body burns alcohol before it burns carbs, protein, and fat — including body fat:

    The Journal of Clinical Investigation 1988: Ethanol causes acute inhibition of carbohydrate, fat, and protein oxidation and insulin resistance [randomized trial; moderate evidence]

  15. This is mainly based on clinical experience of low carb clinicians [weak evidence]

  16.  This is mainly based on the clinical experience of low carb clinicians [weak evidence]

    There’s also a published study showing that avoiding artificially-sweetened drinks helped overweight people lose weight and improve their insulin sensitivity:

    The AmericanJournal of Clinical Nutrition 2015: Effects on weight loss in adults of replacing diet beverages with water during a hypoenergetic diet: a randomized, 24-wk clinical trial [randomized trial; moderate evidence]

  17. Research has confirmed this effect for people of all ages, although to a greater extent for men than women:

    International Journal of Obesity and Related Metabolic Disorders 1995: Resting metabolic rate and cardiovascular disease risk in resistance- and aerobic-trained middle-aged women [non-randomized study; weak evidence]

    Journal of the American Dietetic Association 2001: Effects of habitual physical activity on the resting metabolic rates and body compositions of women aged 35 to 50 years [non-randomized study; weak evidence]

    Medicine and science in sports and exercise 2001: Effect of strength training on resting metabolic rate and physical activity: age and gender comparisons [non-controlled study; weak evidence]

    Journal of Applied Physiology 1985: Strength training increases resting metabolic rate and norepinephrine levels in healthy 50- to 65-yr-old men [non-controlled study; weak evidence]

  18. In studies, resistance training has been shown to consistently improve insulin sensitivity in adults, including people with diabetes and postmenopausal women. Improving insulin sensitivity may make weight loss easier:

    Diabetes Care 2005: Twice-weekly progressive resistance training decreases abdominal fat and improves insulin sensitivity in older men with type 2 diabetes [non-controlled study; weak evidence]

    Journal of Strength and Conditioning Research 2012: Insulin sensitivity after maximal and endurance resistance training. [non-controlled study; weak evidence]

    The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 1996: Resistive training increases insulin action in postmenopausal women [non-controlled study; weak evidence]

  19. This is based on Dr. Naiman’s clinical experience.[very weak evidence]

  20. This is based on Dr. Hallberg’s clinical experience.[very weak evidence]

  21. Obstetrics and Gynecology Clinics of North America 2018: Sleep, health, and metabolism in midlife women and menopause: food for thought [overview article; ungraded]

  22. Psychoneuroendocrinology 2017: Habitual sleep quality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women [observational study; very weak evidence]

    Sleep Science 2015: Interactions between sleep, stress, and metabolism: From physiological to pathological conditions [overview article; ungraded]

  23. Some people eat more in response to stress and higher cortisol levels than others:

    Psychoneuroendocrinology 2001: Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior [non-randomized study; weak evidence]

    In addition, at least one study suggests that women with a tendency to carry weight around the middle may release more cortisol during stressful situations than smaller-waisted women:

    Obesity Research 1994: Stress-induced cortisol response and fat distribution in women [non-randomized study; weak evidence]

  24. Personality and Individual Differences 2014: Stress and emotional eating: The mediating role of eating dysregulation [observational study; very weak evidence]

  25. This is based on consistent clinical experience of low carb practitioners. [weak evidence]